15:00 Registration & Welcome Coffee
16:45 Opening Session
16:45 Welcome & Opening Remarks - Elisa Oricchio, ISREC@EPFL Director — Elisa Oricchio
17:00 Keynote Speaker : The Neuroscience of Childhood Gliomas — Michelle Monje
18:00 Melanoma brain metastasis and the mechanisms of adaptation — Arianna Baggiolini
18:30 Neural mechanisms of brain tumor progression and therapy resistance — Frank Winkler
19:00 Opening Cocktail
08:55 Session 1
08:55 Chair 1 : Denis Migliorini
09:00 Breast tumor heterogeneity and metastasis: Act locally, think globally — Momo Bentires-Alj
09:30 Short Talk : Coordinate and on-demand tumor-antigen uptake and DC activation by chimeric antigen receptor — Yahya Mohammadzadeh
09:45 Targeting the Oncogenic State of RAS with Tri-Complex Inhibitors — Mallika Singh
10:15 Coffee Break
10:45 Lineage Plasticity: An Emerging Mechanism of Acquired Resistance to Cancer Therapy — Charles Sawyers
11:15 Short Talk : Gene regulatory Network inference reveals p63 as a key protumoral master regulator in luminal FGFR3-mutated bladder cancers — Isabelle Bernard-Pierrot
11:30 Systemic perturbation of cellular interactions in the tumor microenvironment — Andreas Moor
12:00 Poster Pitch x 4
12:15 Poster Session 1
12:15 Stand-up Lunch & Poster Session 1
12:30 Meet the Editors Lunch
13:40 Session 2
13:40 Chair 2 : Johanna Joyce
13:45 Studying evolution in renal cancer — Samra Turajlic
14:15 Short Talk : Blocking long-chain fatty elongation triggers anti-tumor immunity — Justine Epiney
14:30 Short Talk : Logic-Gated DLL3-Targeted SynNotch CAR T Cells for Overcoming Antigen Heterogeneity in Small Cell Lung Cancer — Celine Prange
14:45 Mechanisms regulating stem cell plasticity during tumor initiation — Cédric Blanpain
15:15 Coffee Break & Poster Session 1 continued
16:30 Stromal and immune plasticity shape the metastatic microenvironment — Neta Erez
17:00 Short Talk : Mobilization of Tumor-Infiltrating Exhausted CD8⁺ T Cells Toward Long-Term Memory Fate — Rongrong Li
17:15 Myeloid cells : Uncovering conserved functions shaping cancer immunity — Mikaël Pittet
09:25 Session 3
09:25 Chair : Giovanni Ciriello
09:30 New Therapeutic Targets for Acute Myeloid Leukaemia — Kristian Helin
10:00 Short Talk : Pks+ E. coli triggers intestinal stem cell plasticity and early onset colorectal cancer — Stefanie Gerstberger
10:15 Coffee Break
10:45 Somatic Evolution as a Lens into Human Biology and Disease — Dan Landau
11:15 Transcription Factors in Cancer: how they work (and how to get rid of them in therapy) — Nicolas Thomä
11:45 Poster Pitch x 4 — András Hatos, Davey Li, Elena Guido Vinzoni, Elisa Sorrenti
12:00 Poster Session 2
12:00 Stand-up Lunch
13:40 Session 4
13:40 Chair : Sebastian Waszak
13:45 Twisting the Genome: Oncohistones and the 3D Chromatin Code of Cancer — Prof. Nada Jabado
14:15 Short Talk : Optimizing Glioblastoma CAR T Cell Therapy Through Neoadjuvant Delivery and Post-Resection TME Modulation — Martin Pedard
14:30 Short Talk : Peripheral glia drive the initiation of cutaneous squamous cell carcinoma — Sofia Micheli
14:45 From Stem Cells in Leukemia to Neurons in Pancreatic Cancer — Andreas Trumpp
15:15 Coffee Break & Poster Session 2 continued
16:25 Chair : Freddy Radtke
16:30 Creating therapeutic strategies targeting genetically complex leukemia — Fumihiko Ishikawa
17:00 Plasticity of stem-cell like CD8+ T cells in tumors — Werner Held
18:00 Free Evening
08:55 Session 5
08:55 Chair : Miki De Palma
09:00 Dissecting mechanisms of tumor suppression by imaging live mice — Sara Gallini
09:30 Short Talk : SoxC transcription factors are oncoembryonic regulators of colon development and cancer — Tosca Dalessi
09:45 One upon a time there was the perfect anti-cancer target YAP — Georg Halder
10:15 Coffee Break
10:45 Lipid nanoparticle-formulated mRNA as cancer therapy — Damya Laoui
11:15 Short Talk : HPV16-Expressing Tumors Release Multiple IL-1 Ligands to Orchestrate Systemic Immunosuppression Whose Disruption Enables Efficacy of a Therapeutic Vaccine — Morgane Lecointre
11:30 Exploring the Role of Vascular Specialization in Cancer — Tatiana Petrova
12:00 Poster Pitch x 4
12:15 Poster Session 3
12:15 Stand-up Lunch & Poster Session 3
13:55 Session 6
13:55 Chair : Michal Bassani
14:00 Decoding Tumor and Microenvironmental Mechanisms Behind Immune Escape and Recurrence of ovarian cancers — Denarda Dangaj
14:30 Short Talk : Disruption of nonsense-mediated mRNA decay enhances anti-tumour immunity — Roberto Vendramin
14:45 Short Talk : Improving donor selection for hematopoietic stem cell transplantation through in-depth immunopeptidome characterization — Julien Racle
15:00 Coffee Break and Poster Session 3 continued
15:30 Keynote Speaker : T cell recognition of human cancer – cracking the code — Ton Schumacher
16:30 Closing Remarks, Elisa Oricchio, ISREC@EPFL Director — Elisa Oricchio
16:40 Closing Dinner